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In this interview, Dr Louise Olde Nordkamp, a device cardiologist at Amsterdam University Medical Center, discusses the long-term findings of the PRAETORIAN XL trial—a follow-up study comparing transvenous and subcutaneous implantable cardioverter-defibrillators (ICDs). Building on the original PRAETORIAN trial, this extended 8-year analysis evaluated device-related complications and confirmed that subcutaneous ICDs carry fewer major and lead-related complications. Dr Olde Nordkamp highlights the clinical relevance of these results, supporting broader consideration of subcutaneous ICDs in patients without pacing indications.
In this Q&A, Dr Zheng reflects on the power of collaborative mentorship, the creative rewards of scientific discovery, and the promise of precision medicine in reshaping the future of cardiomyopathy care
In this Q&A, Dr Sanghavi shares reflections on the mentors who inspired her, the personal challenges she has overcome and her hopes for a future in which sex-based differences in cardiovascular disease are better understood and acted upon.
June was a dynamic month in cardiovascular medicine, marked by notable regulatory approvals and clinical trial progress across several therapeutic areas. Advances in hypertension management, lipid lowering and cardiometabolic care continue to shape the treatment landscape, while evolving data in pulmonary arterial hypertension underscore the importance of ongoing innovation. This month’s roundup highlights the latest developments poised to impact clinical practice and patient outcomes.
The touchCARDIO journal Heart International has once again seen an increase in its Journal Impact Factor (JIF), rising from 1.9 in 2024 to 2.3 in 2025.
This August, Boston will host one of the most influential gatherings in cardiovascular medicine as the American Society for Preventive Cardiology (ASPC) convenes its 2025 Congress on Cardiovascular Disease Prevention. Set for 1–3 August 2025 at the Omni Boston Hotel at the Seaport, Boston, MA, USA, the meeting will bring together global experts, showcase cutting-edge research, and feature more than 200 abstract posters.
The EEA’s Environmental Noise in Europe 2025 report confirms that chronic exposure to noise is a major contributor to cardiovascular and metabolic disease, linked to tens of thousands of premature deaths annually. In this expert interview, Prof. Thomas Münzel highlights the biological mechanisms involved, the inadequacy of current noise thresholds, and the urgent need to integrate environmental noise into clinical guidelines, risk assessments, and public health policy.
Cardiovascular medicine stands at a pivotal crossroads—shaped by rapid advances in precision therapies, a deepening understanding of disease mechanisms, and an urgent imperative to address global health disparities. As the burden of cardiovascular disease continues to evolve, so too ...
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an inexorably progressive and ultimately fatal cardiomyopathy characterized by the deposition of misfolded transthyretin (TTR) in the form of amyloid fibrils within the myocardium.1 Transthyretin amyloid (ATTR) fibrils are insoluble protease-resistant beta-pleated sheets that are ...
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac abnormality characterized by left ventricular hypertrophy and diastolic dysfunction, primarily attributed to mutations in genes that encode sarcomeric proteins.1,2 The disease manifests in two broad phenotypes: obstructive HCM (oHCM), defined by dynamic left ...
The foramen ovale, an obligatory channel, allows placental oxygenated blood to directly reach the fetal arterial circulation and remains patent in 25% of the adult population.1Â Patency provides a potential gateway for venous emboli to reach the arterial circulation, potentially resulting ...
Physician burnout is at a critical point. In this episode, Nicky speaks with Dr Alfred Atanda about why so many physicians are burning out and what can be done to change the trend. From personal experience to system-wide solutions, Dr Atanda shares valuable insights on improving physician well-being and building a more effective healthcare culture.
What if your medical degree could launch more than a clinical career? In this candid and compelling read, Dr Jon Edelson shares his lessons for early-career clinicians ready to think beyond the bedside and explore the business of medicine.
Early-career cardiologists and researchers face a complex landscape: they must navigate the increasing clinical complexity of cardiovascular disease, stay abreast of rapid scientific developments and manage the pressures of clinical, academic and personal responsibilities. Recognising the need for greater support, ...
May 2025 saw several significant developments in the field of cardiology, including new regulatory approvals, long-term clinical trial data and important findings from late-breaking studies. This roundup highlights the latest updates across structural, interventional and heart failure therapies, with implications for ...
The ACT-EARLY clinical trial has dosed its first participant in an effort to prevent variant transthyretin amyloidosis (ATTRv) in genetically at-risk individuals. By evaluating the selective TTR stabilizer, acoramidis, in asymptomatic carriers, the study aims to delay or halt disease onset. With approximately 600 participants, ACT-EARLY marks a pivotal step toward shifting ATTRv care from reactive treatment to proactive prevention.
Functional status refers to an individual’s ability to carry out different levels of activities to meet the needs of daily living.1 Patients with heart failure (HF) commonly have poor functional status that is affected by a number of physical, ...
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