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Cardiovascular medicine stands at a pivotal crossroads—shaped by rapid advances in precision therapies, a deepening understanding of disease mechanisms, and an urgent imperative to address global health disparities. As the burden of cardiovascular disease continues to evolve, so too does the need for nuanced, evidence-based approaches that span the full spectrum of care: from prevention […]

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Samuel Stempfel, Heli Tolppanen, Valérian Valiton

Conduction system pacing (CSP) is being increasingly adopted as a more physiological alternative to right ventricular and biventricular pacing and is an integral part of the European Heart Rhythm Association (EHRA) core curriculum for the device specialist.1–6 Left bundle branch ...

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In this Q&A, we talk to Dr Nadia Chaher shares insights into her career so far, her experiences and the most exciting current innovations in cardio-imaging.

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Yasser M Sammour, Muhammad Faraz Anwaar, Francisco Cabral-Amador

Tricuspid regurgitation (TR) is a frequent finding on echocardiography, with detection rates reaching up to 86% across the different ranges of severity, with moderate or greater TR being reported in at least 6–8% of patients.1–3 The prevalence of TR increases with age, ...

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Cardiovascular disease (CVD) continues to be the leading cause of death on a global scale. Nearly 18 million people died from CVD in 2019, accounting for about one-third of all deaths globally.1 The primary cause of CVD-related death and morbidity is ischaemic ...

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Clinically relevant tricuspid regurgitation (TR) is a common disorder, affecting approximately 4% of people 75 years of age or older.1 If left untreated, severe TR results in volume overload and right ventricular remodelling. This eventually leads to symptomatic right-sided heart failure, along ...

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Ventricular tachycardia (VT) ablation presents a challenging and growing area of focus in the realm of complex ablation, with promises of improved patient’s quality of life and clinical outcomes.1,2 Classic approaches to VT ablation centered on arrhythmia induction and ...

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Cardiac complications constitute a common cause of morbidity and mortality in the perioperative period, contributing to over a third of perioperative deaths.1 More than 230 million major surgeries are performed annually worldwide, with older patients representing an increasing proportion of the ...

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A significant proportion of patients with atrial fibrillation (AF) who have a high stroke risk are currently being treated with oral anticoagulation (OAC), including direct oral anticoagulants (DOACs) and vitamin K inhibitors (VKAs).1 It is well known that the increased ...

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Mitral valve (MV) disease includes either mitral regurgitation or mitral stenosis or both. The incidence and prevalence of valvular heart disease is increasing with the increasing population age. Degenerative MV disease poses a global burden with a prevalence of 18.1 million ...

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Nishant Sharma, Ayaaz K Sachedina, Sachin Kumar

The global prevalence of aortic stenosis (AS) has steadily increased over the past several decades.1 In high-income countries, degenerative calcific aortic valve disease is the primary aetiology for AS, whereas chronic rheumatic valve disease and infective endocarditis remain more common ...

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The PREDICT LAA trial aimed to examine whether cardiac computed tomography- based FEops HEARTguideâ„¢ computational modelling would benefit clinical outcomes when planning for left atrial appendage (LAA) closure. In this touchCARDIO interview, we speak with Dr Ole De Backer (Rigshospitalet, ...

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Coverage from: TCT Highlights

When performing percutaneous left atrial appendage (LAA) closure, challenges arise that impact clinical outcomes and cardiac computed tomography (CCT)- based patient-specific computational simulations provide device-host interactions. In this touchCARDIO interview, we speak with Dr Ole De Backer (Rigshospitalet, Copenhagen ...

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Despite improved treatment of atherosclerotic cardiovascular disease, coronary artery disease (CAD) remains the leading cause of death and disability worldwide.1 Treatment of traditional risk factors, mainly low-density lipoprotein (LDL) cholesterol, is the foundation of atherosclerotic risk reduction. However, a considerable ...

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Cryptogenic stroke (CS) is a brain infarction that cannot be clearly attributed to cardioembolism, large-vessel atherosclerosis or small artery disease, despite extensive clinical evaluation.1 It represents approximately one-third of all ischaemic strokes worldwide.2 Stroke represents a major public health crisis, ...

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Jared D Romeo, Michael J Bashline, Jeffrey A Fowler

Tricuspid regurgitation (TR) is a complex disease with several independent causes. Consequently, outcomes and response to therapy vary widely. Severe or progressive TR often results in gradual right ventricular (RV) failure and is associated with poor long-term outcomes.1 Most cases ...

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Available evidence from randomized studies suggests that most bifurcation lesions are best managed with a provisional stenting (PS) approach, as this is associated with fewer complications, simpler procedures and better outcomes, compared with elective double stenting.1–6 However, the Achilles’ heel ...

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Tomoya T Hinohara, Michael J Reardon, Sachin S Goel

Transcatheter-based therapies have become central to the treatment of valvular heart disease, particularly aortic stenosis.1–5 The first transcatheter aortic valve replacement (TAVR) was performed in 2002 and, in two short decades, TAVR has become a mainstay for the treatment of aortic ...

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A common complication of endovascular repair of an abdominal aortic aneurysm (EVAR) is the persistence of blood flow outside the lumen of the endoprosthesis, known as an endoleak. Endoleaks are a potentially lethal complication and occur following up to 25% of ...

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