Background. QT dispersion (QTd) is increased in patients with dilated cardiomyopathy.
Increased QTd has been associated with the risk of sudden death. We studied: a) the relation
between QTd on 12-lead ECG and QTd-ECG Holter; b) the relation between QTd apex
(QTda) and QTd end (QTde) on ECG Holter and the risk of ventricular arrhythmias in patients with
Methods and Results. 65 patients with dilated cardiomyopathy (33 idiopathic and 32 post-ischemic etiology; NYHA II-III) were studied. We divided the patients into: Group A -patients with not-sustained ventricular arrhythmias-; and Group B -patients without arrhythmias-. A significant direct correlation between QTd calculated from 12-lead ECG and from ECG Holter was found in all patients. QTda/24h was not significantly different in the two groups (Gr.A 59.9±7.8 msec vs Gr.B 53.6±8.4 msec p=ns) while QTde/24h was significantly higher in Group A (Gr.A 81.9±5.9 msec vs Gr.B 44.5±6.8 msec; p<0.005). In post-ischemic etiology (32 pts; 17 with arrhythmias) the correlation between QTde/24h and ventricular arrhythmias was confirmed (Gr.A 81.4±7.8 msec vs Gr.B 42.6±6.2 msec p<0.002).
Conclusions. ECG Holter recordings can evaluate QTd as well as the QTd on 12-lead ECG. An increased QTde/24h seems to be correlated with the occurence of ventricular arrhythmias in patients with dilated cardiomyopathy and can then be a useful tool to select patients at high risk for sudden death. (Heart International 2006; 2: 33-8)
QTdispersion, ECG-Holter, Ventricular arrhythmias, Dilated cardiomyopathy, Sudden death
Elia De Maria, MD, Via Tebaldini, 5, Sant’Eufemia, 25135 Brescia – Italy, email@example.com
Share this Article
Related Content In Electrophysiology
66/An unexpected block – working up the young patient with unexplained atrioventricular block
European Journal of Arrhythmia & Electrophysiology. 2021;7(Suppl. 1):abstr66
Introduction: The development of atrioventricular block can be a sign of specific cardiac and medical pathologies including cardiac sarcoidosis, vasculitis and thyroid disease. There are no comprehensive guidelines to help facilitate a standardised workup for the younger patient with AV block, and the timing and relative yield of different investigative parameters. We sought to explore […]
70/The impact of the COVID-19 pandemic on cardiac rhythm management services at 2 major UK centres
European Journal of Arrhythmia & Electrophysiology. 2021;7(Suppl. 1):abstr70
Introduction: The COVID-19 pandemic has had a major impact on healthcare services, however the effect has been heterogeneous. We collated cardiac rhythm management (CRM) service provision data from two specialist cardiothoracic centres in the UK without Eds, the Liverpool Heart and Chest Hospital (LHCH) and Royal Papworth Hospital (RPH). We describe the impact of the […]
Are There Enough Data to Safely Withdraw Anticoagulation After Atrial Fibrillation Catheter Ablation?
European Journal of Arrhythmia & Electrophysiology. 2019;5(2):82–6 DOI: https://doi.org/10.17925/EJAE.2019.5.2.82
The global disease burden of atrial fibrillation (AF) is considerable, and a significant proportion is attributable to the associated thromboembolic risk. The pro-thrombotic environment resulting from AF accrues a five-fold increase in stroke risk, with the arrhythmia implicated in 30% of all strokes.1,2 Evaluating thromboembolic risk should be a primary concern for any healthcare practitioner […]
Journal articles and more to your inbox
Get the latest clinical insights from touchCARDIOSign me up!