Professor Martin Borggrefe is the Director of Cardiology at the University Medical Centre Mannheim at the University of Heidelberg. He has a special interest in cardiac arrhythmias – from the electrocardiogram to basic science. Over the last decade, Professor Borggrefe has developed an interest in so-called ‘channelopathies’, which are primary electrical diseases of the heart and affect structurally normal and functioning hearts. In this field he has discovered several novel entities, such as the short QT syndrome along with other J point elevation diseases which usually affect young people who are otherwise healthy. Professor Borggrefe was among the first physicians who developed radiofrequency catheter ablation, publishing the first paper describing ablation of a patient with Wolff-Parkinson-White syndrome using radiofrequency in 1986.