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This corrects the article: “Ioannou A. Evolution of Disease-modifying Therapy for Transthyretin Cardiac Amyloidosis. Heart International. 2024;18(1):30-37”. Two typography errors were included incorrectly due to an editorial error. In Table 1, “eplontersen” was incorrectly written as “eplomtersen”. This has been corrected in the text. In the section “Eplontersen”, the administration schedule should be written as […]

Steven Messe, TCT 2022: Sentinel® cerebral protection system efficacy in reducing all stroke/disabling stroke, the PROTECTED-TAVR trial (a neurologist’s perspective)

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Published Online: Oct 10th 2022

The PROTECTED-TAVR trial studied the efficacy of using an embolic protection device (Sentinel® cerebral protection system) during transcatheter aortic valve replacement in reducing the incidence of stroke/disabling stroke. In this touchCARDIO interview, we speak with Dr Steven Messe (University of Pennsylvania, Philadelphia, PA, USA) to give a Neurologist’s perspective on the findings of the PROTECTED-TAVR study. 

The presentation entitled ‘Clinical Implications of PROTECTED TAVR: A Neurologist’s Perspective’ was delivered at the Transcatheter Cardiovascular Therapeutics (TCT) conference, 16 – 19, September 2022.

Questions:

  1. What is the definition of disabling stroke? (0:13)
  2. Could you give us a brief overview of the PROTECTED-TAVR study? (2:03)
  3. What were the findings of the PROTECTED-TAVR study in terms of incidence of all stroke and disabling stroke? (3:25)
  4. Why was the stroke rate lower than expected? (5:07)
  5. What were the conclusions in terms of future use of the Sentinel® cerebral protection system? (6:36)

Disclosures: Steven Messe is a consultant for Boston Scientific Corporation and EmStop.

Support: Interview and filming supported by Touch Medical Media. Interview conducted by Danielle Crosby.

Filmed as a highlight of TCT 2022

Access more content on Stroke here and Devices here

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