Marked prolongation of QRS duration after initiation of dronedarone therapy

The landscape of managing atrial fibrillation (AF), the most common cardiac arrhythmia and leading cause of stroke, has undergone a period of change following the development of various treatment modalities and risk-modifying strategies designed to mitigate the risk of stroke in patients with AF.1,2 In this expert interview, Tony D Grayson and Carol Hughes highlight the role of direct […]

Catheter ablation has emerged as an effective strategy for the treatment of atrial fibrillation (AF), even becoming a first-line option for selected patients.1 Pulmonary vein isolation (PVI) is the cornerstone of this procedure. Ablation beyond PVI is often practised, but scientific evidence from randomized clinical trials is still controversial.2–8 Point-by-point radiofrequency (RF) ablation has been, by […]

Heart failure (HF) and atrial fibrillation (AF) are inexorably linked. They frequently coexist and share common risk factors, including ageing, hypertension, diabetes, obesity, sleep apnoea and coronary disease.1–4 Over half of patients with HF develop AF at some point,5 and when AF occurs, it is associated with an increase in total mortality of up to 40%.6 In addition, […]