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Congenital Conditions
touchEXPERT OPINIONS
Pompe disease: Expanding manifestations and evolving management
Prof. Damara Ortiz, Prof. Virginia Kimonis, Prof. Loren Pena Watch Time: 35 mins

Watch leading experts discuss recent developments in Pompe disease, including refined understanding of phenotypes and multisystem clinical manifestations emerging in the era of enzyme replacement therapy (ERT). The impact on paediatric patients and their caregivers is also explored, alongside approaches to further optimize multidisciplinary management of Pompe disease.

Learning objectives
Learning Objectives
  • Discuss how successful ERT has led to the new phenotype of infantile-onset Pompe disease
  • Describe the multisystem disorders of late-onset Pompe disease
  • Explain the approaches that are being used to address the unmet treatment needs for Pompe disease
Hypertension
touchPANEL DISCUSSION
Medical therapy for CTEPH: What is the standard of care in 2020?
Prof. Irene Lang, Prof. Nick Kim, Prof. Hiromi Matsubara Watch Time: 30 mins

Watch a panel of internationally renowned chronic thromboembolic pulmonary hypertension (CTEPH) experts discuss medical therapy for CTEPH, and consider the current standard of care using case-based studies to provide practical guidance on the optimal clinical management of patients with CTEPH.

Learning objectives
Learning Objectives
  • Discuss best practice for the multidisciplinary assessment of CTEPH
  • Apply medical therapy for inoperable patients with CTEPH
  • Perform medical therapy for patients with post-operative persistent/recurrent symptomatic disease

    • More From The Conference Hub

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    View highlights and coverage from leading international Cardio congresses

    More From Learning Zone

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    Medical education and communication on key topics in the area of Cardio. Content in this section is sponsored by the pharmaceutical industry.

    Hypertension
    touchEXPERT BRIEFING
    Updates and new guidelines in statin therapy
    Prof. Alberico Catapano, Dr Alan Brown, Prof. Kausik Ray Watch Time: 25 mins

    Watch clinical specialists from Europe and the USA discuss techniques for the management and treatment of patients with high LDL-C levels, recorded during the ESC Congress 2019, Paris, France.

    Learning objectives
    Learning Objectives
    • Understand the importance of the ACC/AHA 2018 and ESC 2019 guidelines for management of blood cholesterol/dyslipidaemias with respect to clinical practice
    • Know the risks and benefits of statin treatment with respect to the risk for type 2 diabetes
    • Understand the potential for abnormal liver function and metabolic syndrome and be aware of drug-drug interaction as most statins are metabolized via the cytochrome P450 pathway
    • Know that the PROVE IT and REAL-CAD trials show that high-dose statin therapy is superior to moderate or low dose in cardiovascular event reduction
    • Understand that combination therapy gives an additional reduction in LDL levels and that statin dose should be titrated to risk

    Latest Journal Articles

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    Read the latest articles from our peer reviewed Cardio journals published by touchCARDIO

    Foreword – European Journal of Arrhythmia & Electrophysiology. 2020;6(1):8
    Norbert Guettler

    Welcome to the summer edition of European Journal of Arrhythmia & Electrophysiology. The COVID-19 pandemic is proving extremely challenging for patients with arrhythmia, as well as cardiologists and electrophysiologists. As new data continue to emerge on the impact of COVID-19 on arrhythmias, new management strategies are evolving. This edition begins with a review by Guettler, […]

    Heart Failure
    Explaining Sex Differences in Cardiac Resynchronisation Therapy Outcome
    Alwin Zweerink, Elise Bakelants, Cornelis P Allaart

    European Journal of Arrhythmia & Electrophysiology. 2020;6(1):17-23 DOI: https://doi.org/10.17925/EJAE.2020.6.1.17

    Over the past years, several reports have drawn attention to the need to consider sex-specific differences in cardiac resynchronisation therapy (CRT). Most importantly, there is growing concern on the underrepresentation of women in CRT landmark trials which laid the foundation for present guidelines. Patients with symptomatic heart failure, reduced left ventricular ejection fraction (LVEF) ≤35% […]

    Congenital Conditions
    Pulmonary Regurgitation – Results from the Harmony Transcatheter Pulmonary Valve Trial
    John Cheatham

    Heart International. 2020;14(2):Online ahead of journal publication

    Moderate-to-severe congenital heart disease, which requires specialist cardiology care, is present in around 6/1,000 live births.1 Patients born with congenital heart defects often require surgery in early life and a consequence of this initial surgical repair is pulmonary regurgitation. The severity of pulmonary regurgitation can worsen over time and present more frequent symptoms, and may […]

    Cardiovascular Disease
    Ratio of Serum Aspartate to Alanine Aminotransferase as a Marker of Isolated Coronary Artery Ectasia and its Severity
    Danesh Soltani, Samira Jafari, Amir Sobh-Rakhshankhah

    Heart International. 2020;14(1):43–8 DOI: https://doi.org/10.17925/HI.2020.14.1.43

    The exact aetiology of coronary artery ectasia (CAE) has yet to be fully elucidated; however, some underlying aetiologies such as atherosclerosis and microvascular abnormalities in coronary arteries have been proposed.1,2 Over the past few years, several inflammatory markers have been introduced as indicators of CAE and its severity. There is an association between the development of […]

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    Taking a balanced and practical view of the current clinical landscape in Cardio is at the heart of touchCARDIO and the journals we produce.

    The European Journal of Arrhythmia & Electrophysiology and Heart International are double-blind peer reviewed by at least two independent experts in the field to ensure articles are balanced, objective and relevant to the day-to-day clinical setting.

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