Effect of left ventricular hypertrophy on long-term survival of patients with coronary artery disease following percutaneous coronary intervention
The impact of left ventricular hypertrophy (LVH) on survival among patients with established coronary artery disease (CAD) is not well understood. We sought to evaluate the effect of LVH on the survival of patients with CAD following percutaneous coronary intervention (PCI). Three hospitals in New York City contributed prospectively defined data on 4284 consecutive patients undergoing PCI. Allcause mortality at a mean follow-up of three years was the primary endpoint. LVH was present in 383 patients (8.9%). LVH patients had a greater prevalence of hypertension (88% vs. 68%, p<0.001), vascular disease (21% vs. 6.6%, p=0.001), and prior heart failure (10% vs. 5.5%, p<0.001). LVH patients presented less often with one-vessel disease (38% vs. 50%, p=0.040) and more often with two- (34% vs. 29%, p=0.014) or three-vessel (22% vs. 18%, p=0.044) disease. Ejection fractions and angiographic success were similar in both groups. In-hospital mortality did not differ between groups. At three-year follow-up, the survival rate for patients with LVH was 86% vs. 91% in patients without LVH (log-rank p=0.001). However, after adjustment for differences in baseline characteristics using Cox proportional hazards analysis, LVH was found not to be an independent predictor of mortality (hazard ratio, 0.93; 95% confidence interval, 0.68-1.28; p=0.67). We conclude that LVH at the time of PCI is not independently associated with an increase in the hazard of death at three years.
Angioplasty, stent, left ventricular hypertrophy, survival.
David L. Brown, Division of Cardiovascular Medicine, Stony Brook University Health Sciences Center T 16-080, Stony Brook, NY 11794-8171, USA. E-mail: david.brown@stonybrook. edu
Share this Article
Related Content In Interventional Cardiology
FOREWORD – HEART INTERNATIONAL – VOLUME 16 ISSUE 2 – 2022
Welcome to the latest issue of Heart International. Cardiovascular science continues to evolve at an impressive rate, and the range of articles presented here highlights cutting-edge technology and innovation within cardiology. We begin with a commentary by Divaka Perera on the REVIVED study, which evaluated whether percutaneous coronary intervention could improve outcomes in patients with […]
FOREWORD – HEART INTERNATIONAL – VOLUME 16 ISSUE 1 – 2022
Heart International. 2022;16(1):1
Welcome to the latest issue of Heart International. We are delighted to bring you another excellent issue, full of the varied and expert articles that you can expect from our authors. We begin with some exciting news. We are delighted to announce that Heart International has been accepted for listing in PubMed, one of the most widely accessible […]
FOREWORD – HEART INTERNATIONAL – VOLUME 15 ISSUE 2 – 2021
Heart International. 2021;15(2) DOI: https://doi.org/10.17925/HI.2021.15.2.62
Welcome to the latest issue of Heart International. The global coronavirus disease 2019 (COVID-19) pandemic has presented numerous challenges that have altered all areas of health care, including cardiology. Despite these challenges, the past year has shown significant innovation across the spectrum of cardiac care, as demonstrated in the diverse range of articles in this issue. COVID-19 […]
Journal articles and more to your inbox
Get the latest clinical insights from touchCARDIOSign me up!