An Introduction to Cardiovascular Disease
Cardiovascular diseases (CVDs) are the number one cause of death globally, taking an estimated 17.9 million lives each year. CVDs describe a number of conditions affecting the heart and circulation, including coronary heart disease, angina, congenital heart disease, hypertension and stroke. The huge and ever-increasing burden of CVDs on individuals and healthcare systems shows the urgent ongoing need for treatments and preventive measures.
Browse the content below where leading experts discuss the latest data in video interviews and short articles from our conference hub, and browse the selection of peer-reviewed articles from our journal portfolio. If you are looking to learn more about the impact of these developments on patient outcomes, our educational activities are a great resource.
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Cardiovascular Disease Content
Wolfgang Linke, ESC 2021 – Key Pathomechanisms of TTNtv-dilated Cardiomyopathy
Dr Wolfgang Linke (Professor and Chair of Physiology, University Hospital of Münster, Münster, Germany) kindly shared his thoughts on the titin gene TTNtv and dilated cardiomyopathy from the virtual ESC Congress 2021. Questions What is known about the correlation between variants in the titin gene (TTNtv) and the incidence of dilated cardiomyopathy (DCM), and what […]
Stephen Nicholls, ESC 2021 – the HUYGENS Study
Prof. Stephen Nicholls (Professor of Cardiology, Monash University, Melbourne, Australia) kindly shared his thoughts on the impact of PCSK9 inhibitors on lipid-lowering therapy, the effects of statins on coronary atherosclerotic plaques and the HUYGENS study from the virtual ESC Congress 2021. Questions What has been the impact of PCSK9 inhibitors on lipid-lowering therapy, and what […]
Jordan Strom, ESC 2021 – Analysis of the Risks of Moderate and Lesser Aortic Stenosis
Dr Jordan Strom (Director of Echocardiographic Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA) kindly shared his thoughts on his recent analysis of clinical trial and administrative claims data on patients with untreated aortic stenosis from the virtual ESC Congress 2021. Questions What are the aims and scope of your current […]
Jordan Strom, ESC 2021 – Untreated Aortic Stenosis
Dr Jordan Strom (Director of Echocardiographic Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA) kindly shared his thoughts on the prognosis of people with untreated aortic stenosis from the virtual ESC Congress 2021. Questions What is known about the prognosis of people with untreated aortic stenosis? (0.29) How have advances in […]
Kazem Rahimi, ESC 2021 – the Blood Pressure Lowering Treatment Trialists Collaboration
Dr Kazem Rahimi (Professor of Cardiovascular Medicine and Population Health, University of Oxford, Oxford, UK) kindly shared his thoughts on the Blood Pressure Lowering Treatment Trialists Collaboration (BPLTTC), its aims, and the benefits of antihypertensive medicines in older people from the virtual ESC Congress 2021. Questions Could you tell us a little about the Blood […]
Darryl Leong, ESC 2021 – Cardiometabolic Risk Factors and COVID-19
Dr Darryl Leong (Cardiologist, The Population Health Research Institute, McMaster University, Hamilton, ON, Canada) kindly shared his thoughts on the association between cardiometabolic risk factors and COVID-19 outcomes from the virtual ESC Congress 2021. Questions What has recent data taught us about the association between cardiometabolic risk factors and COVID-19 outcomes? (0.15) On the basis […]
Medical Therapy for Secondary Prevention of Atherothrombotic Events in Peripheral Artery Disease
Heart International. 2021;15(1):14-19 DOI: https://doi.org/10.17925/HI.2021.15.1.14
Peripheral artery disease (PAD) is a severe manifestation of systemic atherosclerotic disease that commonly refers to lower-extremity arterial involvement. The global burden of PAD is estimated to involve over 200 million patients, with prevalence increasing by 24% over the past decade.1 In contrast to myocardial infarction and stroke, which are declining in the USA, the […]
Dual Antiplatelet Therapy in Patients with High Cardiovascular Risk
Heart International. 2021;15(1):26-36 DOI: https://doi.org/10.17925/HI.2021.15.1.26
Coronary artery disease (CAD) is encountered on a daily basis in the field of medicine. Between 2009 and 2012, the global prevalence of CAD was 154 million, based on data from the Global Burden of Disease study; for the same period in the USA, it was approximately 15.5 million, based on data collected by the […]
The Role of Rilonacept in Recurrent Pericarditis
Heart International. 2021;15(1):20-25 DOI: https://doi.org/10.17925/HI.2021.15.1.20
Pericarditis is the most common form of pericardial disease, with an incidence of 27.7 cases per 100,000 population per year.1 Approximately 15–30% of patients with acute pericarditis will have a first recurrence within 18 months despite optimal medical therapy. Half of these patients will fail to achieve complete remission and will continue to have recurrent […]
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