Cardiac tumors in a tertiary care cancer hospital: clinical features, echocardiographic findings, treatment and outcomes
Abstract
Overview
Cardiac tumors are a rare entity, comprised of
tumors with diverse histology and natural history.
We report the clinical characteristics,
echocardiograhic findings, therapy and outcome
of 59 patients with primary and metastatic
cardiac tumors. Our institutional echocardiogram
data base from 1993 through 2005 was
reviewed to identify patients diagnosed with
intra-cardiac tumor. A total of 59 patients with
cardiac tumors were identified and included in
the study. The patients’ characteristics, presenting
symptoms, diagnostic tests, location, histology
of the tumor, treatment and the one year
survival rate of this population was collected
from the medical records. Of the 59 cardiac
tumor cases, 16 (27%) were primary cardiac
tumors and 43 (73%) were secondary cardiac
tumors. The most common primary tumor was
sarcoma affecting 13 (81%) of the 16 cases. Of
these, 5 patients were angiosarcoma, 5 unclassified
sarcoma, one myxoid sarcoma and 2
malignant fibrous histiocytoma. The mean age
at presentation was 41.1 years, and the most
common location was right atrium affecting 6
cases (37.5%). The most common symptom of
dyspnea was present in 10 (62.5%) cases.
Eleven (25.6%) of the 43 secondary cardiac
tumors were metastasis from renal cell carcinoma.
The mean age at presentation was 55.4
years. Right atrium was the most frequent location
affecting 18 (42%) of the 43 patients. The
most common presenting symptom was dyspnea
in 15 (35%) cases. For both primary and
secondary tumors, dyspnea was the most common
symptom and right atrium was most frequently
involved. Sarcoma was the most common
primary cardiac tumor while metastasis
from renal cell carcinoma was the most common
secondary tumor.
Keywords
Cardiac tumors, tertiary care cancer hospital.
Article Information
Correspondence
Syed Wamique Yusuf, Department of Cardiology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1451, Houston, TX 77030, USA. Tel. +1.713.792.8472 – Fax: +1.713.745.1942. E-mail: syusuf@mdanderson.org
Received
2011-06-24T00:00:00
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