An Introduction to Thrombosis
Thrombosis refers to the formulation of a thrombus within a blood vessel, disrupting the normal blood flow through the circulatory system. Anticoagulation therapy with vitamin K-antagonists such as warfarin with heparin was the long-standing gold-standard treatment for thrombotic conditions. However, the introduction of direct oral anticoagulants changed the treatment paradigm and are now the first-line treatment of choice for eligible patients.
Browse the content below where leading experts discuss the latest data in video interviews and short articles from our conference hub, and browse the selection of peer-reviewed articles from our journal portfolio.
Andexanet Alfa and its Clinical Application
Heart International. 2020;14(1):20-3 DOI: https://doi.org/10.17925/HI.2020.14.1.20
The factor Xa (FXa) inhibitors apixaban, rivaroxaban and edoxaban, together with the thrombin inhibitor dabigatran, are collectively referred to as non-vitamin K antagonist (or direct) oral anticoagulants (NOACs). FXa inhibitors are widely used for stroke prevention in patients with nonvalvular atrial fibrillation,1 and for the treatment and prevention of deep vein thrombosis and pulmonary embolism.2,3 In patients […]
Improved Dosing and Administration of Rivaroxaban when Prescribed by a Cardiologist
Heart International. 2019;13(1):24–7 DOI: https://doi.org/10.17925/HI.2019.13.1.24
Rivaroxaban is a direct factor Xa inhibitor indicated to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation (AF), treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE). Furthermore, it is prescribed for risk reduction and prophylaxis for DVT and PE following hip or knee replacement surgery and […]
Purvi Parwani, Mamas Mamas, Martha Gulati, ESC 2018 – Social Media and Cardiology
Dr Purvi Parwani (Assistant Professor of Medicine, Loma Linda University Health, Loma Linda, CA, USA), Professor Mamas Mamas (Professor of Cardiology, University of Keele, Keele, UK) and Dr Martha Gulati (Head of Cardiology, University of Arizona College of Medicine, Phoenix, AZ, USA) discuss social media in cardiology. Filmed at ESC 2018, Munich. View more content […]
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