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130/His-bundle pacing the feasibility of upgrading patients with a high ventricular pacing burden

Published Online: October 3rd 2008 European Journal of Arrhythmia & Electrophysiology. 2019;5(Suppl. 1):abstr130
Authors: C Little (Presenting Author) - The Great Western Hospital, Swindon, UK; M Swift - The Great Western Hospital, Swindon, UK; P Foley - The Great Western Hospital, Swindon, UK; B Stegemann - Aston University, Aston, UK; B Chandrasekaran - The Great Western Hospital, Swindon, UK
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Background: His-bundle pacing (HBP) is rapidly growing in popularity as an alternative to right ventricular (RV) pacing. One major disadvantage of HBP is the high capture threshold. Achieving optimal His-bundle (HB) pacing location is technically challenging. Suboptimal location often requires a higher pacing stimulus voltage and pulse widths are also frequently extended to 1.0 ms. Both has a negative impact on the device longevity. This could then lead to more generator changes, as associated with an increased risk of infection and other complications leading to an increased cost to the NHS. There have been no long-term studies, specifically looking at temporal changes of HBP thresholds and the impact this may have on the battery longevity.

Method: Fifty consecutive patients were included in this retrospective study, all of whom a Medtronic 3830-69 cm – His lead. All patients received a Medtronic Azure pacemaker. The mean age was 74.6 years and 79% were male. Pacing thresholds were collected during implant, at the 2-week device check, at the 6-month follow up and 12-month follow up – as per departmental protocol. The trends were then analysed.

Results: Pacing threshold were initially high (see Table 1) and continuously decreased throughout the 1-year follow-up.

Conclusion: Though the initial threshold in HBP is high at implant – this data shows it decreases over time thus improving longevity. Thresholds appear stable once it passes the 6-month follow up. This positive find should help encourage more His implants. Larger studies are needed to confirm these results. Implant related trauma causes initial rise in HBP threshold. Is there room for improvement on implant practice, leads, dexamethasone, objective assessment of damage (assessing the injury potential).

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European Journal of Arrhythmia & Electrophysiology. 2021;7(Suppl. 1):abstr43

Introduction: Cardiac tamponade is a high morbidity complication of transseptal puncture (TSP). We examined the incidence and predictors of TSP-related cardiac tamponade (TRCT) for all patients undergoing left atrial ablation at our centre from 2016-2020. Methods: Patient and procedural variables were extracted retrospectively. Cases of cardiac tamponade were scrutinised to adjudicate TSP culpability. Adjusted multivariate […]

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