Home > News > 26/Body surface potential mapping is no more sensitive than 12-lead ECG for measuring ventricular repolarisation in obese individuals
Arrhythmia
Read Time: 2 mins

26/Body surface potential mapping is no more sensitive than 12-lead ECG for measuring ventricular repolarisation in obese individuals

Published Online: September 27th 2010 European Journal of Arrhythmia & Electrophysiology. 2020;6(Suppl. 1):abstr26
Authors: R Davidson (Presenting Author) - Imperial College London, London; KHK Patel - Imperial College London, London; M Brezitski - Imperial College London, London; B Statton - Imperial College London, London; A Berry - Imperial College London, London; X Li - Imperial College London, London; S Purkayastha - Imperial College London, London; J Cousins - Imperial College London, London; D O’Regan - Imperial College London, London; NS Peters - Imperial College London, London; JS Ware - Imperial College London, London; FS Ng - Imperial College London, London
Quick Links:
Article
Article Information
Article:

Background: Obesity is associated with pro-arrhythmic electrocardiographic (ECG) abnormalities, such as corrected QT (QTc) prolongation and increased QT dispersion (QTd), which confer a greater risk of ventricular arrhythmia and sudden cardiac death. Few studies have assessed specific measures of repolarisation (T-peak-to-T-end interval (Tpe) or the Tpe/QT, Tpe/QTc, Tpe/JT or Tpe/JTc ratios) in obesity. Owing to greater thoracic coverage, body surface potential mapping (BSPM) may provide greater sensitivity than 12-lead ECG to assess repolarisation abnormalities associated with obesity.

Aims: We aimed to assess differences in measures of ventricular repolarisation and its dispersion between obese and normal-weight individuals using 12-lead ECG. Secondly, we aimed to perform BSPM at rest and during recovery from exercise to assess whether BSPM is more sensitive than 12-lead ECG for detecting differences in ventricular repolarisation between obese and normal-weight individuals.

Methods12-lead ECGs from 22 obese (BMI-35.6±6.7) and 44 age-sex matched normal-weight (BMI-22.5±1.6) individuals were analysed. 252-lead BSPM was performed in 6 obese (BMI-39.8±9.1) and 6 age-sex matched normal-weight (BMI-23.8±0.9) individuals at rest and 2 minutes following exercise. QTd was defined as the standard deviation of QT intervals (QTstd).

Results: Obese individuals had significantly prolonged QT (380±25 vs 367±26, p<0.05), QTc (404±24 vs 379±21, p<0.0001) and JTc (304±23 vs 285±22, p<0.001) intervals at rest compared to normal-weight individuals. There were no differences in the JT or Tpe intervals or the Tpe/QT, Tpe/QTc, Tpe/JT and Tpe/JTc ratios between the groups. There were no differences in the QTstd between obese and normal-weight individuals using 12-lead ECG (19±4.3 vs 19±4.2, p>0.05) or 252-lead BSPM (20±5.7 vs 19±3.8, p>0.05). QTc prolongation was no more pronounced following exercise in obese compared to normal-weight individuals.

Conclusion: Obesity is associated with delayed ventricular repolarisation reflected by QTc and JTc interval prolongation. BSPM does not provide greater sensitivity than 12-lead ECG for measuring differences in ventricular repolarisation in obese individuals. Recovery from exercise does not unmask abnormalities of ventricular repolarisation in obese individuals which are not present at rest.

Article Information:

Further Resources

Share this Article
Related Content In Arrhythmia
  • Copied to clipboard!
    accredited arrow-downarrow_leftarrow-right-bluearrow-right-dark-bluearrow-right-greyarrow-right-orangearrow-right-whitearrow-right-bluearrow-up-orangeavatarcalendarchevron-down consultant-pathologist-nurseconsultant-pathologistcrosscrossdownloademailexclaimationfeedbackfiltergraph-arrowinterviewslinkmdt_iconmenumore_dots nurse-consultantpadlock patient-advocate-pathologistpatient-consultantpatientperson pharmacist-nurseplay_buttonplay-colour-tmcplay-colourAsset 1podcastprinter scenerysearch share single-doctor social_facebooksocial_googleplussocial_instagramsocial_linkedin_altsocial_linkedin_altsocial_pinterestlogo-twitter-glyph-32social_youtubeshape-star (1)tick-bluetick-orangetick-whiteticktimetranscriptup-arrowwebinar Department Location NEW TMM Corporate Services Icons-07NEW TMM Corporate Services Icons-08NEW TMM Corporate Services Icons-09NEW TMM Corporate Services Icons-10NEW TMM Corporate Services Icons-11NEW TMM Corporate Services Icons-12Salary £ TMM-Corp-Site-Icons-01TMM-Corp-Site-Icons-02TMM-Corp-Site-Icons-03TMM-Corp-Site-Icons-04TMM-Corp-Site-Icons-05TMM-Corp-Site-Icons-06TMM-Corp-Site-Icons-07TMM-Corp-Site-Icons-08TMM-Corp-Site-Icons-09TMM-Corp-Site-Icons-10TMM-Corp-Site-Icons-11TMM-Corp-Site-Icons-12TMM-Corp-Site-Icons-13TMM-Corp-Site-Icons-14TMM-Corp-Site-Icons-15TMM-Corp-Site-Icons-16TMM-Corp-Site-Icons-17TMM-Corp-Site-Icons-18TMM-Corp-Site-Icons-19TMM-Corp-Site-Icons-20TMM-Corp-Site-Icons-21TMM-Corp-Site-Icons-22TMM-Corp-Site-Icons-23TMM-Corp-Site-Icons-24TMM-Corp-Site-Icons-25TMM-Corp-Site-Icons-26TMM-Corp-Site-Icons-27TMM-Corp-Site-Icons-28TMM-Corp-Site-Icons-29TMM-Corp-Site-Icons-30TMM-Corp-Site-Icons-31TMM-Corp-Site-Icons-32TMM-Corp-Site-Icons-33TMM-Corp-Site-Icons-34TMM-Corp-Site-Icons-35TMM-Corp-Site-Icons-36TMM-Corp-Site-Icons-37TMM-Corp-Site-Icons-38TMM-Corp-Site-Icons-39TMM-Corp-Site-Icons-40TMM-Corp-Site-Icons-41TMM-Corp-Site-Icons-42TMM-Corp-Site-Icons-43TMM-Corp-Site-Icons-44TMM-Corp-Site-Icons-45TMM-Corp-Site-Icons-46TMM-Corp-Site-Icons-47TMM-Corp-Site-Icons-48TMM-Corp-Site-Icons-49TMM-Corp-Site-Icons-50TMM-Corp-Site-Icons-51TMM-Corp-Site-Icons-52TMM-Corp-Site-Icons-53TMM-Corp-Site-Icons-54TMM-Corp-Site-Icons-55TMM-Corp-Site-Icons-56TMM-Corp-Site-Icons-57TMM-Corp-Site-Icons-58TMM-Corp-Site-Icons-59TMM-Corp-Site-Icons-60TMM-Corp-Site-Icons-61TMM-Corp-Site-Icons-62TMM-Corp-Site-Icons-63TMM-Corp-Site-Icons-64TMM-Corp-Site-Icons-65TMM-Corp-Site-Icons-66TMM-Corp-Site-Icons-67TMM-Corp-Site-Icons-68TMM-Corp-Site-Icons-69TMM-Corp-Site-Icons-70TMM-Corp-Site-Icons-71TMM-Corp-Site-Icons-72