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81/Outcomes of patients with structural heart disease with VT storm directly to a tertiary centre experience

Published Online: September 27th 2010 European Journal of Arrhythmia & Electrophysiology. 2020;6(Suppl. 1):abstr81
Authors: N Ahluwalia (Presenting Author) - St Bartholomew’s Hospital, London; A Graham - St Bartholomew’s Hospital, London; M Orini - University College London, London; JS Gill - St Bartholomew’s Hospital, London; S Sporton - St Bartholomew’s Hospital, London; A Chow - St Bartholomew’s Hospital, London; RJ Hunter - St Bartholomew’s Hospital, London; P Lambiase - St Bartholomew’s Hospital, London; M Dhinoja - St Bartholomew’s Hospital, London
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Introduction: Ventricular tachycardia (VT) storm is a medical emergency characterised by clustered episodes of ventricular arrhythmia seen in patients with structurally abnormal hearts. Effective management of this complex, life-threatening phenomenon requires an understanding of arrhythmia mechanisms and the multi-modality treatment options. Although ablation can be life-saving, it is associated with significant risk in this sick cohort and considered patient selection is essential. Direct admission of patients with recurrent ICD shocks or incessant VT to a tertiary electrophysiology centre from the community can provide early expert-led decision-making.

Methods: VT storm was defined as three or more separate episodes of sustained VT within 24 hours, each requiring termination by an intervention. Incessant VT was defined as sustained VT for more than one hour, refractory to, or recurring promptly after, termination by intervention. These patients were eligible for direct admission to St Bartholomew’s Hospital from the community under the Electrophysiology on-call service. Admissions via this pathway between August 2018 and February 2019 were screened. Additional cases were identified from a manual search of the hospital’s catheter ablation database between June 2016 to August 2018. Cox regression analysis was performed to identify associations between pre-specified variables.

Results: 89 patients met inclusion criteria with an average age of 68±17 years, of whom 82 (92%) were male. Shock-free survival was seen in 62 (70%) patients at 12 months. 1-year mortality was 22.5% with no significant difference between patients presenting with incessant VT or VT storm (HR 1.84 [0.75-4.53] (p=0.19)). Patients selected to undergo ablation had similar outcomes at 1-year to those who managed non-invasively (HR 0.63, [0.25-1.59] p=0.33). CKD at baseline (HR 3.36 [1.07-10.59] p=0.04) and admission duration (HR 1.08, [1.03-1.14], p<0.01) were associated with mortality after multi-variate analysis. CKD was associated with mortality in subgroup analysis in patients with incessant VT or VT storm. We did not identify significant association with age or re-do procedure.

Conclusion: Occurrence of VT storm is a poor prognostic marker and concurrent CKD may confer greater risk. Further extrapolation of findings and associations is limited as patient’s management was non-random and based on informed decision-making. Although the outcomes between non-invasive and invasively managed cohorts was similar, these may represent very different patient groups, with patients at both ends of the disease severity spectrum potentially managed more conservatively. Outcomes are similar to other published International experiences and it demonstrates feasibility of early specialist engagement, in keeping with consensus recommendations. Further study and sub-group analysis could guide strategy choice and would be valuable to support decision-making.

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43/Cardiac tamponade as a complication of transseptal puncture: associations and operatordependent variables during left atrial ablation at Barts Heart Centre
E Maclean (Presenting Author) - St Bartholomew’s Hospital, London; K Mahtani - St Bartholomew’s Hospital, London; C Butcher - St Bartholomew’s Hospital, London; N Ahluwalia - St Bartholomew’s Hospital, London; M Finlay - St Bartholomew’s Hospital, London; S Honarbakhsh - St Bartholomew’s Hospital, London; A Creta - St Bartholomew’s Hospital, London; A Chow - St Bartholomew’s Hospital, London; V Sawhney - St Bartholomew’s Hospital, London; V Ezzat - St Bartholomew’s Hospital, London; MJ Earley - St Bartholomew’s Hospital, London; M Dhinoja - St Bartholomew’s Hospital, London; S Sporton - St Bartholomew’s Hospital, London; MD Lowe - St Bartholomew’s Hospital, London; PD Lambiase - St Bartholomew’s Hospital, London; F Khan - St Bartholomew’s Hospital, London; SY Ahsan - St Bartholomew’s Hospital, London; RJ Hunter - St Bartholomew’s Hospital, London; RJ Schilling - St Bartholomew’s Hospital, London; O Sega - St Bartholomew’s Hospital, London Read Time: 2 mins

European Journal of Arrhythmia & Electrophysiology. 2021;7(Suppl. 1):abstr43

Introduction: Cardiac tamponade is a high morbidity complication of transseptal puncture (TSP). We examined the incidence and predictors of TSP-related cardiac tamponade (TRCT) for all patients undergoing left atrial ablation at our centre from 2016-2020. Methods: Patient and procedural variables were extracted retrospectively. Cases of cardiac tamponade were scrutinised to adjudicate TSP culpability. Adjusted multivariate […]

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